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- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorLee AronsohnChuck LorreStarsJon CryerAshton KutcherAngus T. JonesA hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorStephanie SavageJosh SchwartzStarsBlake LivelyLeighton MeesterPenn BadgleyPrivileged teens living on the Upper East Side of New York can hide no secret from the ruthless blogger who is always watching.
- CreatorPaul T. ScheuringStarsDominic PurcellWentworth MillerAmaury NolascoA structural engineer installs himself in a prison he helped design, in order to save his falsely accused brother from a death sentence by breaking themselves out from the inside.
- CreatorMike KelleyStarsMadeleine StoweEmily VanCampGabriel MannAn emotionally troubled young woman sets out to exact revenge against the people who wronged her father.
- CreatorLeila GersteinStarsRachel BilsonJaime KingCress WilliamsNew Yorker and new doctor Zoe Hart accepts an offer from a stranger, Dr. Harley Wilkes, to work in his medical practice in Bluebell, Alabama. She arrives to find that he has died and left half the practice to her in his will.
- CreatorMark SchwahnStarsChad Michael MurrayJames LaffertyHilarie Burton MorganHalf-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina.
- CreatorDarren StarJeff JudahGabe SachsStarsShenae Grimes-BeechTristan Mack WildsAnnaLynne McCordA Kansas family relocates to Beverly Hills, where their two children adapt to the infamous social drama of West Beverly Hills High.
- CreatorChris FedakJosh SchwartzStarsZachary LeviYvonne StrahovskiJoshua GomezWhen a computer geek inadvertently downloads critical government secrets into his brain, both the CIA and the NSA assign an agent to protect him and exploit his newfound skills.
- CreatorTim KringStarsJack ColemanHayden PanettiereMilo VentimigliaCommon people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.
- CreatorSteven S. DeKnightStarsAndy WhitfieldLucy LawlessManu BennettThe life of Spartacus, the gladiator who lead a rebellion against the Romans. From his time as an ally of the Romans, to his betrayal and becoming a gladiator, to the rebellion he leads and its ultimate outcome.
- CreatorCraig SilversteinStarsMaggie QShane WestLyndsy FonsecaA rogue assassin returns to take down the secret organization that trained her.
- CreatorJ.J. AbramsAlex KurtzmanRoberto OrciStarsAnna TorvJoshua JacksonJohn NobleAn F.B.I. agent is forced to work with an institutionalized scientist and his son in order to rationalize a brewing storm of unexplained phenomena.
- CreatorNick WautersStarsJason RitterSarah RoemerIan Anthony DaleWhen a man goes looking for his missing girlfriend, he stumbles upon a government conspiracy that is bigger than the President himself.
- CreatorMatt OlmsteadNick SantoraStarsDomenick LombardozziBrooke NevinMalcolm GoodwinA squad of U.S. marshals team up with cons (former fugitives) to work together on tracking down prison escapees in exchange for getting time off their sentences.
- CreatorSteven LilienElizabeth SarnoffBryan WynbrandtStarsSarah JonesJorge GarciaJonny CoyneIn 1963, all the prisoners and guards mysteriously disappear from Alcatraz. In the present day, they resurface and a secret agency are tasked with re-capturing them.
- CreatorDoug EllinStarsKevin ConnollyAdrian GrenierKevin DillonFilm star, Vince Chase, navigates the vapid terrain of Los Angeles with a close circle of friends and his trusty agent.
- CreatorMatthew MillerStarsIoan GruffuddAlana De La GarzaJoel David MooreDr Henry Morgan, a medical examiner, works with his partner Detective Jo Martinez, to solve criminal cases. Along the way, he tries to uncover the mystery to his 200-year-old immortality.
- CreatorMarc CherryStarsTeri HatcherFelicity HuffmanMarcia CrossSecrets and truths unfold through the lives of female friends in one suburban neighborhood after the mysterious suicide of a neighbor.
- CreatorDarren StarStarsSarah Jessica ParkerKim CattrallKristin DavisFour female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- CreatorConstance M. BurgeStarsHolly Marie CombsAlyssa MilanoBrian KrauseThree Halliwell sisters discover that they are descendants of a line of good female witches and are destined to fight against the forces of evil, using their combined power of witchcraft known as the "Power of Three".
- CreatorSteven BaigelmanStarsJeremy SistoTaissa FarmigaGabriel LunaA pair of LAPD detectives track down serial killers terrorizing the Sunset Strip.
- CreatorJanet TamaroStarsAngie HarmonSasha AlexanderJordan BridgesDetective Jane Rizzoli and Chief Medical Examiner Dr. Maura Isles team up to solve crimes in Boston.