Taught to play guitar by Mr. Scurti, an older Italian gentleman.
Has played Gretsch guitars throughout his career and in 1990, he became the first guitarist since Chet Atkins to be honored with a signature-model Gretsch, the "Brian Setzer 6120", now one of an extensive line of Setzer signature models.
Raised in Massapequa, Long Island, New York.
He married DeAnna at the Courthouse in Tallahassee, Florida on Valentine's Day after playing a concert the previous night.
Brian and his ex-wife, DeAnna Madsen, have a son, Cody.