- She got the part in Gone Girl (2014) beating out Natalie Portman, Charlize Theron, Emily Blunt, Abbie Cornish, Olivia Wilde, Julianne Hough, and the film's producer Reese Witherspoon all of whom either auditioned or were considered for the part.
- Can also speak French and German.
- David Fincher had her undergo a rigorous boxing training with welterweight champion Holly Lawson for her role in Gone Girl (2014).
- She applied to multiple acting schools in university but was rejected by all of them.
- Plays the piano and cello.
- Turned down the role of Rita Skeeter on Harry Potter and the Goblet of Fire (2005) in order to star in Pride & Prejudice (2005). The role went to Miranda Richardson.
- Graduated with a 2:1 (upper second class degree = 2nd Honors = Magna Cum Laude) in English Literature from Oxford University's Wadham College.
- Has been in a long-term relationship with Robie Uniacke since December 2009. They have two sons together.
- Was 5 months pregnant with her son Solo when she completed filming on Jack Reacher (2012).
- She played two different characters in the James Bond franchise: Miranda Frost in Die Another Day (2002) and Pussy Galore in BBC4's 2010 radio adaptation of "Goldfinger". Die Another Day co-star Toby Stephens played James Bond in the BBC radio series.
- An only child, her parents are Julian and Caroline Pike. Julian is a professional opera singer, whilst Caroline is a concert violinist.
- Gave birth to her 2nd child at age 35, a son Atom Uniacke at home on December 2, 2014. Child's father is her long-term boyfriend, Robie Uniacke.
- Gave birth to her first child at age 33, a son named Solo Uniacke on 6 May 2012. The child's father is her long-term boyfriend, Robie Uniacke.
- Won the Award for Best Debut at the 2003 Empire Awards for her performance as Miranda Frost in Die Another Day (2002).
- Was considered to star as Grace Kelly in Grace of Monaco (2014).
- Beat out Saffron Burrows, Alicia Silverstone, and Sophie Ellis-Bextor for her role in Die Another Day (2002).
- She was one of the top contenders for the role of Lois Lane in Man of Steel (2013), but chose to do Wrath of the Titans (2012) instead. The role eventually went to Amy Adams.
- Was engaged to Joe Wright, having met when he directed her on the set of Pride & Prejudice (2005), after he proposed to her on Lake Como in Italy (September 2007-June 2008).
- Joe Wright called off their engagement shortly before their wedding. The "save the date" cards were already sent out. [June 2008].
- In 2014, the press gave her the moniker "Bond Girl to Gone Girl", because of the similar characters she played in both the James Bond film Die Another Day (2002) and in Gone Girl (2014).
- She has said that "China and Chinese culture are very important for my family" and has given herself a Chinese name, Pei Chunhua because she thought the transliteration of her English name is long and not very feminine. She explained she chose the Chinese name because Pei is a traditional Chinese last name, Chun represents the idea of pure and honesty, a characteristic she'd like to embody, and Hua has the same sound as the character meaning flower, as Rosamund means rose of the world.
- Returned to work 4 months after giving birth to her son Solo to begin filming The World's End (2013).
- Went to school in Bristol, England, UK.
- She was friends with Chelsea Clinton while at Wadham College, Oxford. Not only are they both the same height (5' 9"), they are both fluent in German, and they are both only children.
- Was considered for either Emma Frost or Moira McTaggart in X-Men: First Class (2011).
- The age difference between her and Halle Berry in Die Another Day (2002) - 12 years and 5 months - is the greatest age difference between two Bond girls in one film since Alison Doody and Grace Jones - a difference of 18 years - in A View to a Kill (1985).
- Johnny Depp is one of her favourite actors. She worked with him on The Libertine (2004).
- Nominated for the 2019 Golden Globe Award in the Best Performance by an Actress in a Motion Picture - Drama category for her role as Marie Colvin in A Private War (2018), but lost to Glenn Close for The Wife (2017).
- Her birthday is often reported as being January 27, but she has said this is incorrect. She has not said what the correct date is, only that she is an Aquarius (late January/February).
- Returned to work 10 months after giving birth to her son Atom to begin filming A United Kingdom (2016).
- She and Halle Berry are the only two actresses to play Bond Girls (who bedded Bond) in the official 007 franchise to receive Oscar nominations: Berry won for her performance in Monster's Ball (2001), while Pike was nominated for her work in Gone Girl (2014). Kim Basinger, who starred in Never Say Never Again (1983), also went on to win the Best Supporting Actress Oscar for L.A. Confidential (1997), but her movie is considered non-canon in the 007 franchise. Both Pike and Berry were in the same Bond movie, Die Another Day (2002), and both were nominated in the Best Actress category. Oscar nominee Minnie Driver and Oscar Winner Judi Dench both appeared in the Bond film GoldenEye (1995), but neither played Bond Girls who bedded Bond.
- Turned down the role of Jess Barrett in Focus (2015) that went to Margot Robbie.
- Went to the same school as famous Irish writer Iris Murdoch.
- She has described several times her difficulty in learning how to smoke cigarettes for her role as Marie Colvin in "A Private War", claiming that she had never smoked before. However, she is briefly seen smoking in both "Gone Girl" and an episode of "Foyle's War", and quite frequently in "An Education".
- One of her most memorable teen crushes was of Patrick Dempsey in J.F.K.: Reckless Youth (1993).
- Eton-educated partner Robie Uniacke has 4 children from two broken marriages.
- Auditioned for the role of Danielle in The Words (2012) that went to Olivia Wilde.
- Became friends with Chelsea Clinton, when they were both at Oxford.
- The only time she has acted out giving birth in a movie was in A United Kingdom (2016).
- Making a play on words with the letters of her artistic name ("Rosamund Pike") it obtains "A Supremo Kind".
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