- Brother of actor Cary Elwes and film producer Cassian Elwes.
- His American wife Lewanne was a former New York gallerist who is now occupied with the management and shipping of Damian's work.
- Former brother-in-law of actress Catherine Oxenberg.
- Is a distant relative of the famous Archaeologist Lord Carnarvon, and a distant nephew of Henry VIII Tudor, King of England, as well as he is a distant nephew of his third wife, Jane Seymour.
- Cousin of actress Amanda Elwes.
- His marriage to ex-wife Christina Oxenberg, the second daughter of Princess Elizabeth of Yugoslavia and younger sister of actress Catherine Oxenberg, took place in Jordan.
- Met his wife Lewanne at an art gallery in Los Angeles.
- Mother is interior designer/shipping heiress Tessa Kennedy.
- Older half-brother of Milica Kastner and Dillon Kastner from his mother's marriage with Elliott Kastner.
- Lived in Colombia.
- He petitioned for divorce from Christina Oxenberg. After five years of marriage, they separated in 1991. They were later divorced in 1996, citing the reason for their marital breakdown as "complete emotional and mental incompatibility".
- His father Dominick Elwes and grandfather Simon Elwes were well-known English portrait painters, but in an effort to avoid following in their footsteps, Damian studied screenwriting at Harvard University. In the mid-1980s, however, he began to paint, and soon realized that it was a calling he was powerless to avoid.
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