- Grandson of Joe Keaton and Myra Keaton.
- Son of Buster Keaton and Natalie Talmadge.
- As a teenager, he and his brother, Buster Keaton Jr. would swim in the Pacific Ocean with their next door neighbor, Johnny Weissmuller.
- Nephew of Harry Keaton and Louise Keaton.
- Stepson of Eleanor Keaton.
- Younger brother of Buster Keaton Jr..
- Served in the Coast Guard during World War II before helping establish the Office of Strategic Services (OSS) as an underwater demolition expert.
- Following his parents' divorce, he changed his name to Bob Talmadge from Bob Talmadge Keaton.
- Nephew of Norma Talmadge and Constance Talmadge.
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