During the big shoot out, the window frame that "Sonny" peeks out of goes from damaged to undamaged to being damaged again.
In the rain drenched sequence in which Jeff (Chester Morris) lifts Maria (Jean Arthur) out of the submerged car on the bridge, Maria is wearing galoshes, but in the inserted long shot, her stunt double is not.
After Crane and Black escape prison, the headline in the Herald Sentinel reads "Four States Report Convict Clews" which should read "Clues." Correction: Clew is an obsolete form of clue.