(at around 4 mins) Early in the film, Shawn Wayans's character says that his father is only a few years older than him. Lahmard J. Tate, who plays Ashtray's father, is less than two years older than Wayans. Cuba Gooding Jr. is only 7 years younger than Laurence Fishburne, who played his character's father in Boyz n the Hood (1991).
A trailer for the film included the tagline, "It's the only movie released this year with fourteen words in its title"
(at around 19 mins) Loc Dog warns Ashtray about how promiscuous Dashiki is, saying, "She got more kids than Ms. Wayans." Marlon Wayans is one of ten children. Three of his siblings are in the movie: Kim Wayans, Shawn Wayans, and Keenen Ivory Wayans, who has a cameo.
Ashtray's father is played by Lahmard J. Tate, the older brother of Larenz Tate who played O-Dog in Menace II Society (1993).
(at around 50 mins) When Ashtray and Loc Dog are thrown against the police car, a white Ford Bronco in the background has bloody hand prints on the side. It's a reference to O.J. Simpson's infamous Bronco chase and subsequent trial.