Edward Norton was approached to play Bruce Banner, but he turned it down; he didn't like the script despite being a Hulk fan. He later accepted the role in The Incredible Hulk (2008).
Nick Nolte grew his hair wildly for this movie when he was arrested for drunk driving and photographed for his now-infamous mug shot.
Ang Lee employed the split-screen technique to cinematically mimic the panels of a comic-book page. This required many takes of one scene, which was draining for Eric Bana. It took him four takes to film Banner's first Hulk transformation, and by the time of its completion, he was on the verge of collapse.
Lou Ferrigno: (at around 12 mins) As a security guard. Ferrigno is best known for playing The Hulk in The Incredible Hulk (1978) and a few succeeding projects.
Stan Lee: (at around 12 mins) The creator of the Hulk (1962) appeared as a security guard. Lee ad-libbed his lines.