- George, Lizzie, and Ralph have been released due to an explosion at a Scumlabs facility. The trio begin to destroy all of Scumlabs' bases scattered throughout the world and kill its employees.
- Early one morning at the ScumLabs International Research Facility, Dr Veronica Demonic is broadcasting the news of a possible on-site accident when the Lab suddenly blows sky high!
Later that same day, the city of Peoria, Illinois is visited by three enormous creatures who rampage through the city intent on it's total destruction. The three, who until recently were key members of the Scumlab janitorial staff, have mutated into a giant ape (George), a giant lizard (Lizzy) and a giant Wolf (Ralph).
The trio smash their way through hundreds of cities throughout the world, in an attempt to find and destroy the 12 Scumlab Research Facilities under the control of cigar-chomping billionaire, Eustas Demonic.
Eventually, they meet face-to-face with a self-mutated, gargantuan and disgustingly naked Eustas on the dark side of the moon. Dr. Veronica Demonica, sympathetic to the plight of the misunderstood trio, attempts to return them to normal size with a hasitly assembled "Shrink-Ray", with only limited success. The story ends with the three tiny monsters bouncing happily on Dr Veronica's head & shoulders.
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