Craig Pomeroy has another House as in the Pilot.
The plot of Parker Stevenson having to choose to "grow up" with a well-paying job (lawyer) or stay at the beach is the plot of the movie Lifeguard where Sam Elliott, who was training Parker Stevenson, has to decide the same thing (only he's not a lawyer).
Thomas Ian Nicholas later became a Star in the American Pie Movies.
Shawn Weatherly (Jill) had a guest role in V.I.P. years later. The lead role in V.I.P. was played by Pamela Anderson, who became one of the main actors in later Baywatch seasons.
Billy and his co-star Erika Eleniak formed one of the most iconic couples on the show - and they were also engaged in real life.