When a family annihilator abducts a teen girl, the BAU works the case on either side of the country to save her. But an unlikely connection to a mysterious kit leads to a bigger investigation and at the center of it is Penelope Garcia.
Team hunts an UnSub who severs spinal cords, and uncover a clue from their last case pointing to a serial killer network. To figure out how big this network is, Rossi must convince a reluctant Garcia to return to the BAU.
At the heart of the serial network is Elias Voit. Dangerous psychopath. Manipulative narcissist. Loving father and husband. The team must find all of his kill kits, but one is missing, and the path leads to a bomb in the capitol.
The BAU hunts for the next connection to the serial killer network when they pursue a home invasion team. Alvez and Garcia convince Tyler Green to submit to a cognitive interview to unlock his memories of Sicarius.
The aftermath of the explosion threatens to end the Sicarius case unless the BAU can justify a reason to keep it open. The hunt takes them to a death row inmate - but is he a killer or another one of Sicarius' victims?
With the fate of the Sicarius investigation hanging in the balance, the BAU takes a case in West Virginia, where an UnSub practices his own twisted form of Old Testament vengeance.
Voit's internal struggles with himself lead him to a desperate kidnapping. But Rossi's obsession brings the BAU closer to the truth than they've ever been.
With Rossi in Voit's clutches, he grapples with the limits of his technical know-how and mental strength. As the BAU tightens their grip on Voit, he reveals just how far he's willing to take his deadly crusade.