The character Cybill states she is from Memphis Tennessee which is also the hometown of the actress Cybill Shepherd.
This episode marked Tom Wopat's last appearance as a series regular. Minus any explanation, Wopat's character would appear only sporadically in a handful of episodes through the series' final season.
The title refers to the nickname for New York City - The Big Apple.
Jeff's baby is named Luke. His dog is named Duke. Tom Wopat is best known for playing Luke Duke on The Dukes Of Hazzard.