Dr. Eli says that he was from Johns Hopkins, class of 1848. In fact the Johns Hopkins Hospital opened in 1889 and the medical school opened four years later.
Cloud Dancing uses the word AHO as hello greeting. In truth, that word is Lakota Sioux not Cheyenne and means 'it is good' and is usually used after prayers like Amen.
Dr. Quinn asks Dr. Eli for help. She wants him to perform surgery on Myra. Dr. Quinn's dress is very low cut. For a professional woman from an elite family of Boston the neckline is inappropriate.