In the Desperately Xeeking Xena segment Dr. Frink questions Lucy Lawless on a scene change which involves two different horse breeds. Lucy responds with "A wizard did it" which has since become a popular media trope to explain away continuity errors.
In 'Desperately Xeeking Xena,' the Collector has the following prisoners preserved in Mylar bags: Leonard Nimoy as Spock, Bob Denver as Willy Gilligan, the robot from Lost in Space (1965), Jeri Ryan as Seven-Of-Nine, series creator Matt Groening, Tom Baker as The Fourth Doctor Who, and Yasmine Bleeth as lifeguard Caroline Holden.
The third and final segment, 'Life's a Glitch, Then You Die,' deals with the hysteria caused by the so-called Y2K bug. It was believed that when the date switched from 99 to 00 on most machines, the system would think it was 1900 rather than 2000 and would glitch, crashing all the world's computers. This episode aired about two months before December 31st, 1999.
Ned Flanders wearing "Beatles boots" in the Y2K segment is the first indication we have of his secret obsession with The Beatles, formally revealed in The Bart of War (2003).
Lucy Lawless, though appearing as "herself," speaks in the American accent she used as Xena on Xena: Warrior Princess (1995) instead of her native New Zealand accent.