Ash learns that the next Orange League Gym is located on Navel Island, and decides to head there.
When Team Rocket recites their motto, the regular background music of the motto was not playing.
This is the second dubbed episode to not use the Pokémon logo in the title card when the episode title includes the franchise's name. Starting this episode, the episodes with the franchise's name no longer use the Pokémon logo. The first was Fire Pokémon Big Race! (1997). The accent on the 'e' is also for some reason displayed before the rest of the title.
Tracey references a real person in this episode, Florence Nightingale.
Real fish can be seen in this episode, in the moment before which Nurse Joy is sinking.