While James Hong, Lucy Liu, and Randall Duk Kim reprised their roles from the films for the series, some of the show's other voice actors reprised their roles from the video games.
This is Nickelodeon's first animated series since Avatar: The Last Airbender (2005) to normally use half-hour long episodes.
There are some minor inconsistencies for the coloring of some characters, such as Tigress' eyelids being black instead of white and Shifu's legs being white instead of brown.
This is Nickelodeon's second DreamWorks deal, with the first being The Penguins of Madagascar (2008).
Wallace Shawn and R. Lee Ermey have previously appeared in Pixar's Toy Story franchise.