It was released as a single on November 20 and is the first commercial single in Mayer's career that was not originally released on one of his albums but added to the special edition re-release of his album, Continuum.
In the U.S., it has become the artist's highest charting single, reaching number twelve on the Billboard Hot 100 in May, 2008.
The song earned Mayer another Grammy Award for Best Male Pop Vocal Performance, his fourth win on the category.
Mayer posted the song on his official blog on November 16, 2007.
Chuck Taylor of Billboard called "Say" a "lilting, bittersweet ballad" and said that it "is bound to be another staple for the AC format."