Judy folds the paper cranes for Henry. Henry mentions the book "Sadako and the Thousand Paper Cranes" to Judy. In that book, Sadako has cancer and works to fold 1000 paper cranes while she's in the hospital, as there is a legend that says if a sick person folds 1000 cranes they would soon get well.
This episode features a major reunion between Katey Sagal and Christina Applegate. They worked together nearly 35 years ago on Married...with Children (1987)