Lizzy Caplan could not reprise her role as Casey Klein for the entire third season due to scheduling conflicts with Fleishman Is in Trouble (2022).
Kyle uses Spider-Man as an example to make a point to Roman. Roman is played by Martin Starr who has appeared in the latest Spider-Man trilogy.
James Marsden plays an actor who's done comic book films. Marsden has been in the X-Men series and Superman Returns (2006).