Stewie Griffin references Mila Kunis' real-life friend, Neve Campbell.
Herpes, like HIV, hepatitis, CMV, measles, polio, Ebola, influenza, SARS, mumps, yellow fever, Zika, small pox, rabies, meningitis, chicken pox, rubella, encephalitis, dengue fever, and every other systemic virus in the entire fricking world can be transmitted by direct blood to blood contact (that includes dirty needles from drug use or bad tattoo parlors). Swapping blood is the ultimate, most effective way to transmit infectious diseases.