The case takes place in Atlanta, GA. Automobiles are shown with license plates on the front. Georgia does not use front license plates. Palm trees are also shown in the background in a few scenes. There are no palm trees in Atlanta.
The CDC is referred to as the Center for Disease Control instead of the correct Centers for Disease Control. The sign in front of the CDC also has it spelled incorrectly.
While Hotch was in the editor's office, the second hand on the wall clock is not moving.