Chris prepares to go under the knife as he will be a 'living-donor' for a liver transplant for his son, Charlie. Single father Michael comes into the hospital with his son Josh who has sickle-cell anaemia.
Tijana was born with abnormally small eyes, reducing her vision. First-time parents Charlotte and Dan have only just had baby Lily but she requires surgery to correct a cleft lip and palate.
Rob's given up his job as a HGV driver to become full-time carer for his 4-year-old daughter Chelsea, who has a serious kidney disorder. Shafak has four children one of whom, Eman, also has a kidney problem.
Two teenagers are offered risky procedures that could help them. 16-year-old Rene has sickle cell anaemia and decides whether to have a stem-cell transplant while epileptic Jack is offered brain surgery.
This edition follows parents who have to adjust their hopes for the future of their children following potentially life-threatening accidents. Mollie is knocked down by a car and Rebecca falls from her horse.
A baby born with no eyes has her sockets widened to accommodate prosthetic ones and the parents of an 8-year-old put him forward for a new treatment for his genetic disease.
Evan's family find that he requires an urgent kidney transplant, acts of teenage rebellion threaten the health of Keanu, five-year-old Lewis has swallowed several coins while playing shop with his teddy bears.
10-year-old Louie faces up to the prospect of major heart surgery with courage, while his parents struggle to hide their own fears. Four-year-old Finlay has a nasty cut across his forehead.