This is a remake of the original 2006 film, After the Wedding (2006), starring Mads Mikkelsen (Hannibal, The Hunt, and Dr. Strange), Sidse Babett Knudsen (Westworld and Borgen) and Rolf Lassgård (Downsizing and A Man Called Ove). The original was directed by Susanne Bier (Bird Box and The Night Manager). The original was set in Copenhagen, while the remake is set in New York. In addition the remake has swapped the genders of the three leading characters.
Diane Kruger was originally cast, but had to drop out of the production due to scheduling conflicts. Michelle Williams replaced her.
Julianne Moore and Billy Crudup, who play husband and wife in this movie, also acted together in Trust the Man (2005), in which they play siblings (not love interests). Both After the Wedding (2019) and Trust the Man (2005) were directed by Bart Freundlich, who is married to Julianne Moore.
Michelle Williams and Julianne Moore both previously collaborated on Wonderstruck.