- It was Rose Marie who suggested Morey Amsterdam, a long-time friend of hers, be considered to play the third writer on The Dick Van Dyke Show (1961). The producers of the sitcom had originally planned to hire a younger actor who would play a new writer just starting out in show business, but decided that a show biz veteran like Amsterdam playing an older writer at the end of his career would offer even better comedic possibilities.
- Her husband, musician Bobby Guy, was at one time lead trumpeter for the NBC orchestra on "The Tonight Show".
- Born on the day that the Broadway musical "Rose-Marie" opened.
- Made history as one of the headliners who opened the Flamingo Hotel in Las Vegas, the first of the modern hotel/casinos.
- While married and before the death of her husband, she had a collection of several different colored hair ribbons she wore in her hair, although after his death, she only ever wore black velvet ribbons in her hair.
- Wanted to leave The Dick Van Dyke Show (1961) after her husband died on May 27, 1964, but was talked out of it by director John Rich, and continued until the end of the sitcom's run on June 1, 1966.
- According to the liner notes for the CD of the "Gypsy" soundtrack, Rose Marie was on the "short list" of possible dubbers for Rosalind Russell (Lisa Kirk ultimately was chosen.).
- She was awarded a Star on the Hollywood Walk of Fame for Television 7083 Hollywood Boulevard in Hollywood, California on October 3, 2001.
- On stage from age three as "Baby Rose Marie, she dropped the "Baby" at age 15.
- Her mother, Stella Gluscak Curley, had young Rose Marie when she was only age 16. Years later, her mother passed away on November 6, 2000, having lived to age 93, which was almost exactly the age her daughter had died, 17 years later, on December 28, 2017.
- Her always wearing a black velvet hair bow had some personal significance on which Rose Marie had refused to elaborate. However, one of the many interesting facts found out about over time is the reason why Rose Marie always wore that small, black, velvet ribbon in her hair while working. Supposedly it was an homage to the love of her life, jazz trumpeter Bobby Guy, who died from a mysterious blood disease at age 48 on May 27, 1964.
- She had two separate acting careers - one as "Baby Rose Marie" in the 1920s, and the other, which began in the 1940s.
- According to Sylvia Miles, Rose Marie got the job for which she is best known (Sally Rogers on The Dick Van Dyke Show (1961)) after Miles pulled out after the pilot.
- Toured for over eight years in the musical revue, "4 Girls 4", with Rosemary Clooney, Helen O'Connell and Margaret Whiting. After the death of Margaret Whiting on January 10, 2011, Rose Marie was the last remaining member of the four.
- Was into Italian cooking and knitting (on The Dick Van Dyke Show (1961), she occasionally would be seen knitting in the office).
- According to her Twitter account, she was a huge fan of Stephen King and had read all of his books.
- Friends with Dick Van Dyke and Jerry Lewis.
- Lifelong friends with Randy West, from 1981 until Marie's death on December 28, 2017.
- Following her death, she was interred at Glen Haven Memorial Park in Sylmar, Los Angeles, California.
- Mother of Georgiana Guy Rodrigues.
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