Doctor: "If you had even the slightest sense of humor, you'd realize I was making a small joke." Seven: "Very small." This is reminiscent of a scene between Chekov and Spock in The Trouble with Tribbles (1967).
The Borg interior that Seven sees through a pair of turbolift doors was a single frame of a visual effect sequence from Star Trek: First Contact (1996).
At this point in the series Voyager has traveled 15,000 light years toward home.
This episode marks the final appearance of the type 3 phaser on Star Trek: Voyager, a form of rifle that was introduced in Star Trek: First Contact (1996). All phaser rifles subsequently shown on the series are the compression phaser rifle.
At one point, Seven reads Paris' body temperature as 97.6. This is a rare use of the Fahrenheit scale.