Agnese's condition rapidly deteriorates and Andrea receives the support of the whole ward to discover what's happening. The accusations against him about the falsification of data on pharmaceutical trials jeopardize his career.
Andrea Fanti, a brilliant Head of Internal Medicine, has his life turned upside down following an accident. He survives, but loses his memory of the last twelve years of his life. When he wakes up, he struggles to remember his life.
A special episode set ten years earlier. Andrea has an opportunity to make a career jump but it's hard to keep everything together: suddenly finding himself involved in a rivalry with a colleague, he risks losing sight of who he really is.
Locked in the ward in a forced quarantine, the doctors fight against time to stop a multidrug-resistant bacterium. Doc proposes a drastic and risky solution, but it is Giulia who has to decide.
Andrea is hospitalized in the Internal Medicine ward, hoping that the place most familiar to him will help him recover his memory. Giulia oversees his rehabilitation but finds herself dealing with a different man to the one she knew.
Carolina, suffering from a mysterious illness, is admitted to the hospital, triggering a series of conflicts between her parents that they will have to overcome for her. Meanwhile a flashy influencer attracts the young trainees' attention.