I just saw this film an hour ago and i have to say this is a better drug-related film than requiem for a dream. The film features Tim Roth and Tupac Shakur as two addicts who try to kick the habit after their friend (Thandie Newton) falls into a drug induced coma. After being given the run-around by various clinics and offices, they decide to fall back on some drugs before they get into rehab but are chased through the city by a drug dealer and police officers. Tupac and Roth are a great on-screen duo and the film does a good job of showing the grittier side of drugs and the difficulty of quitting. I highly recommend this film as one of Tupac's best and Roth's most obscure roles. Altogether a great movie.