Quincy gets involved in youth gangs and the probation program after a nine-year old girl is killed in a drive by shooting. A 14-year old boy is set up to take the rap.
When a man dies during bypass surgery, Quincy discovers the operation was performed by a resident instead of the heart surgeon who was to do the procedure.
Quincy revisits old friends and travels to Washington DC in an effort to get the Orphan Drug act passed, and help a young mother suffering from myoclonus.
A new pathologist (Walter Ross) is working in the lab who is disabled. When he looks into a case of electrocution of a handicapped baby he is convinced that the baby was murdered by its father.
Quincy must unravel the mystery of who murdered the town bully in a small community outside of Los Angeles. He runs into opposition as it seems that everyone in town wants to protect the killer, including local law enforcement.
A sick woman with cancer leaves the hospital and dies. Those that have had physical contact with her die. Quincy soon discovers a new virus is the culprit of the deaths and hurries to find the cause.
Michael Moroshima, a cop working undercover with the Asian task force and Sam's best friend, is killed while listening in on a deal between the Yakuza and the Mafia.
A narcissistic psychopath kidnaps the granddaughter of a former Congressman. He says it will be "Divine Retribution" if she dies, and the fault for her death will rest upon the shoulders of the Congressman and Quincy.
After a young girl is found dead along a roadside, Quincy enlists the help of a psychologist in order to determine if the girl committed suicide or if she was murdered by her boyfriend.
When a young man who dies in an industrial accident because he couldn't read the hazard signs. Quincy takes on the problem of adult illiteracy. A problem that hits close to home with Quincy, when he finds that his friend can't read.
A filthy foster home's blamed for the death of a young boy. Quincy tries to start a program, so the boy's brother can be reunited with his troubled family, and a new stable environment be created.