The Fantastic Four stops the Skrulls once again, but Sue ends up in a coma and her dad is framed. The Skurlls also send Super-Skrull again, this time masked as Sue. Meanwhile, Skrull warlord Morrat tries to take over the Skrull empire.
The Fantastic Four help Black Bolt save his people - the Inhumans - who live imprisoned under an unbreakable dome guarded by a simple, but relentless robotic sentry, who misunderstood his orders to protect the Inhumans forever.
Wishing to take over the world, Dr. Doom steals Silver Surfer's power cosmic again and becomes literally unbeatable. The Fantastic Four's figure that the only thing stopping him now is Galactus' power.