The author of the book Katherine Paterson has a cameo as the shop clerk in the bus station scene. The clerk tells Gilly to check out the books.
The screenplay was written by David Paterson, son of the author of the book, The Great Gilly Hopkins, Katherine Paterson.
Danny Glover was originally cast to the role of Mr. Randolph but replaced due to scheduling conflicts.
This is one of two films, starring Octavia Spencer. which has foster care as its primary subject matter. The other film is called Instant Family.