We meet again the whole Cesaroni family, as each member comes to terms with the end of summer and the beginning of a new year - with new expectations, dreams and (the usual) misunderstanding.
Giulio, Cesare and Ezio try to intimidate newcomer Barilon, who (supposedly) owns a a bar that is soon to be opened two steps away from the Bottiglieria.
Ezio and Giulio begins to suspect Cesare may be a killer; meanwhile, Marco and Eva, coming off their first night together, spread the magic of love all around them.
Lucia is craving after taking part in a tango contest with former star dancer Giulio, but he may have lied a little about his former glories in the field.
Giulio is in hospital, recovering from his heart attack. Around him, the usual whirlwind of funny situations, led by the dynamic duo formed by Cesare and Ezio.
Through a dream about Cesare and their father, Giulio finds out he was never meant to be an innkeeper - or was he? Meanwhile, Eva is sad about Marco's departure, blaming her parents for his lover's decision.
The upcoming derby between local teams Garbatella and San Paolo is warming everybody up, including Giulio, which is his team's captain. Nonetheless, his recent health problems are giving him more than one second thought.
Ezio, Cesare and Giulio start a new business, selling wine and sandwiches outside the Colosseum; Eva starts to think she might still feel something for Marco.
A customer at the Bottiglieria tries to take his own life, failing and suffering a memory loss as a consequence. Forced by Cesare, Giulio reluctantly lets the poor guy stay at his house until they find a solution to the problem.
Giulio's team, "La Romulana", is about to move up to a higher league, but Cesare has other plans. Meanwhile, Marco is asked by a well-known radio station to give an interview about his recent YouTube breakthrough.