Some time later, when the pandemic is over, everyone's lives are turned upside down. While Doc seems willing to leave everything, a new internist, a new infectious specialist, but above all a new primary arrives at the hospital.
To treat an incarcerated mother accused of attempting to kill her daughter, Doc must fight against the prejudices of the entire hospital, just as he himself is being targeted by the investigation.
The doctors are busy solving the delicate case of a deaf and blind boy; Cecilia makes Doc an unexpected offer, triggering the jealousy of Agnes and Giulia.
When he is one step away from regaining his primary care, Doc is forced to make a confession in front of the whole department. As doctors try to save the life of a young soldier with unexplained symptoms, Agnes begins to investigate.
Locked in the ward in a forced quarantine, the doctors fight against time to stop a multidrug-resistant bacterium. Doc proposes a drastic and risky solution, but it is Giulia who has to decide.